🧪 6-APB

🧪 6-APB (6-(2-Aminopropyl)benzofuran)

Forensic and Analytical Overview

1. Chemical Identification

Common name: 6-APB
Systematic name: 1-(Benzofuran-6-yl)propan-2-amine
Chemical class: Benzofuran / Amphetamine analogue
Molecular formula: C₁₁H₁₃NO
Molecular weight: ~175.23 g/mol
Structural relation: Structural analogue of MDA (3,4-methylenedioxyamphetamine), with the oxygen bridge replaced by a benzofuran ring system.

2. Background

6-APB, also known as “Benzofury”, first appeared in the early 2010s as a benzofuran-based stimulant and entactogen analogue within the amphetamine class.
It has been a compound of interest in forensic, toxicological, and neurochemical research, owing to its similarity to MDA and MDMA derivatives in structural and receptor-binding characteristics.

While studied in scientific contexts for its interaction with monoamine transporters, 6-APB is not approved for medical or veterinary use and remains subject to legal control in numerous jurisdictions.

3. Analytical Characterization

Laboratory identification techniques include:

• Gas Chromatography–Mass Spectrometry (GC–MS)

• Liquid Chromatography–Mass Spectrometry (LC–MS)

• Infrared (IR) and Raman Spectroscopy

• Nuclear Magnetic Resonance (NMR)

• High-Resolution Mass Spectrometry (HRMS)

Analytical signatures include characteristic fragment ions derived from the benzofuran moiety, with diagnostic peaks confirming the 6-position substitution pattern and secondary amine side chain.

4. Research and Forensic Relevance

6-APB is utilized primarily for:

• Forensic identification and confirmation of benzofuran analogues

• Comparative structure–activity research within substituted amphetamines

• Analytical reference standard preparation

• Toxicological detection method development

5. Legal and Safety Notes

Status: Controlled or listed under NPS legislation in many regions.
Handling: Restricted to authorized laboratories and qualified chemical researchers.
Storage: Maintain in sealed containers, away from light and moisture.
Safety: Employ PPE and adhere to institutional safety standards for handling psychoactive research materials.

6. Summary

6-APB is a benzofuran-based analogue of MDA examined for analytical, forensic, and neurochemical research.
Its inclusion in reference databases enhances forensic identification and understanding of substituted amphetamine analogues.

⚠️ For Research Use Only / Not for Human Consumption
Not intended for medical, veterinary, or household use.
For qualified laboratory applications only.